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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
High

Clinical History:
The patient is a 52 year old with abnormal uterine bleeding

Interpretation:
Endometrial cells are present in a woman >= 40 years of age. Negative for squamous intraepithelial lesion. (See Note)
Note: Endometrial cells after age 40, particularly out of phase or after menopause may be associated with benign endometrium, hormonal alterations and less commonly, endometrial /uterine abnormalities. Clinical correlation is recommended

Cytomorphologic Criteria:
In this field, single cells with abundant eccentric cytoplasm and indented or reniform nuclei characteristic of superficial stromal cells/histiocytes are seen. Histiocytes are often associated with and indistinguishable from superficial stromal cells.

Explanatory Notes:
Endometrial glandular cells were seen in other field(s), and thus endometrial cells were reported. Pap test with only histiocytes/superficial stromal cells should be reported as "Negative for intraepithelial lesion or malignancy." Histiocytes/superficial stromal cells alone do not have independent diagnostic significance and should NOT be reported in the same context as exfoliated glandular cells.

Follow-up:
Endometrial carcinoma in a background of endometrial hyperplasia


See Also: thumbnail for figure JLC-22.jpg
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