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Atlas Interpretation:
Interpreted image
Type of Preparation:
SurePath/ LBP


Clinical History:
42 year old female, menstruating at time of office visit

Endometrial cells are present in a woman >= 40 years of age. Negative for squamous intraepithelial lesion. (See Note)
Note: Endometrial cells after age 40, particularly out of phase or after menopause may be associated with benign endometrium, hormonal alterations and less commonly, endometrial /uterine abnormalities. Clinical correlation is recommended.

Cytomorphologic Criteria:
Cells are in a three dimensional "above the plane" of squamous cells. Nuclei are larger and vacuoles are seen at the periphery of the cell group. Apoptosis is seen easily as dark nuclear material (individual cell necrosis).

Explanatory Notes:
In women 40 or over (or if the age is not provided) exfoliated endometrial cells should be reported. A comment stating "negative for squamous intraepithelial lesion" should be made if applicable. An educational note is recommended explaining the possible significance of exfoliated endometrial cells in women 40 years or older. Such cases are considered "Other" in the General Categorization.

See Also: thumbnail for figure EMS_SP_100_03.jpg
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