Type of Preparation: Conventional Magnification: High Clinical History: A 50 year old woman. No clinical history available Interpretation: Endometrial cells are present in a woman >= 40 years of age. Negative for squamous intraepithelial lesion. (See Note) Note: Endometrial cells after age 40, particularly out of phase or after menopause may be associated with benign endometrium, hormonal alterations and less commonly, endometrial /uterine abnormalities. Clinical correlation is recommended. Cytomorphologic Criteria: Cells occur in small clusters. Small, round nuclei similar in size to a normal intermediate cell nucleus. Inconspicuous or absent nucleoli. Cytoplasm is scant, basophilic and sometimes vacuolated. Cell borders are ill-defined. Explanatory Notes: Endometrial cells may be encountered when evaluating Pap tests. Prior to age 40, exfoliated endometrial cells are not associated with significant endometrial pathology. In women 40 years or older, a small number of women may have uterine abnormalities and usually have symptoms of bleeding. Because menstrual history, menopausal status, clinical symptoms, and endometrial cancer risk factors are often unknown to the laboratory, endometrial glandular cells are reported in all women 40 years and older. Follow-up: Unavailable