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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP

Magnification:
Medium

Clinical History:
43 year old man, HIV+. Anal-rectal sample

Interpretation:
LSIL

Cytomorphologic Criteria:
The classic "koilocyte" as seen on anal cytology.

Explanatory Notes:
Criteria for LSIL are similar to cervical cytology. Note also the cytoplasmic orangeophilia consistent with keratinization, which seems to be more prominent in anal cytology.

Follow-up:
Concurrent bxs showed AIN 1 (mild dysplasia)

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 1 0%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 11 2%
ASC-H # people picked ASC-H 1 0%
LSIL # people picked LSIL 483 97%
HSIL # people picked HSIL 2 0%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 0 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 1 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
499 interpretations were submitted.

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