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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
High
Clinical History:
48 year old woman 2+ years s/p resection, TAH and radiotherapy for colon carcinoma now presents with posterior vaginal lesion
Interpretation:
Adenocarcinoma, extrauterine (metastatic from colonic primary)
Cytomorphologic Criteria:
This group of atypical glandular cells with nuclear pleomorphism, hyperchromasia, and cellular overlap is diagnostic of adenocarcinoma. The tall columnar cells and scattered goblet cells with distended mucin-filled vacuoles are characteristic of colon carcinoma.
Explanatory Notes:
Colon carcinoma is one of the most common secondary tumor encountered in cervical cytology samples. Although metastatic carcinomas to the cervix lack tumor diathesis, direct extension of this tumor from the rectum may be associated with such diathesis.
Follow-up:
Adenocarcinoma of the colon
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Bethesda Interobserver Reproducibility Data:
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