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Atlas Interpretation:
Interpreted image
Type of Preparation:


Clinical History:
48 year old woman 2+ years s/p resection, TAH and radiotherapy for colon carcinoma now presents with posterior vaginal lesion

Adenocarcinoma, extrauterine (metastatic from colonic primary)

Cytomorphologic Criteria:
This group of atypical glandular cells with nuclear pleomorphism, hyperchromasia, and cellular overlap is diagnostic of adenocarcinoma. The tall columnar cells and scattered goblet cells with distended mucin-filled vacuoles are characteristic of colon carcinoma.

Explanatory Notes:
Colon carcinoma is one of the most common secondary tumor encountered in cervical cytology samples. Although metastatic carcinomas to the cervix lack tumor diathesis, direct extension of this tumor from the rectum may be associated with such diathesis.

Adenocarcinoma of the colon

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 0 0%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 0 0%
ASC-H # people picked ASC-H 1 0%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 7 1%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 36 7%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 1 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 1 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 48 10%
Adenocarcinoma # people picked Adenocarcinoma 408 81%
502 interpretations were submitted.

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