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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
Medium
Clinical History:
61 year old female with postmenopausal bleeding
Interpretation:
Adenocarcinoma, Endometrial
Cytomorphologic Criteria:
Loose aggregate of small epithelial cells with slightly enlarged nuclei, small nucleoli, and vacuolated cytoplasm; "watery diathesis" and histiocytes also noted.
Explanatory Notes:
In conventional smears, endometrial adenocarcinoma is more commonly associated with a thin watery diathesis in the smear background in contrast to the bloody, necrotic background associated with endocervical adenocarcinoma.
Follow-up:
Endometrial adenocarcinoma, Grade 1.
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Bethesda Interobserver Reproducibility Data:
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