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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP


Clinical History:
39 year old female, Day 12 of cycle

Adenocarcinoma, Endocervical

Cytomorphologic Criteria:
Cluster of cells enlarged nuclei, macronucleoli and some nuclear membrane irregularities; poorly defined, finely vacuolated cytoplasm; ghost of RBC's and cell debris noted at the edge of the cluster ("clinging diathesis").

Explanatory Notes:
In liquid-based preparations, tumor diathesis may be seen as coagulated necrosis or as debris clinging to the periphery of clusters of abnormal cells.

Endocervical adenocarcinoma

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 59 10%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 1 0%
ASC-US # people picked ASC-US 9 2%
ASC-H # people picked ASC-H 3 1%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 4 1%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 9 2%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 167 29%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 56 10%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 58 10%
Adenocarcinoma # people picked Adenocarcinoma 205 36%
571 interpretations were submitted.

See Also: thumbnail for figure 6_24.jpg
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