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Atlas Interpretation:
Interpreted image
Type of Preparation:
SurePath/ LBP

Magnification:
High

Interpretation:
Endocervical adenocarcinoma in situ (AIS)

Cytomorphologic Criteria:
Numerous abnormal glandular cells arranged singly, in small aggregates and pseudostratified strips. Nuclei are round, oval or elongated with irregular nuclear membranes and small nucleoli. Note the mitotic figure.

Explanatory Notes:
In liquid-based preparations, AIS often presents with pseudostratified strips of cells having short "bird-tail" arrangements.

Follow-up:
Endocervical adenocarcinoma in situ

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 46 9%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 0 0%
ASC-H # people picked ASC-H 5 1%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 5 1%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 2 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 119 22%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 10 2%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 323 60%
Adenocarcinoma # people picked Adenocarcinoma 31 6%
 
541 interpretations were submitted.

See Also: thumbnail for figure DW97.jpg
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