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Atlas Interpretation:
Interpreted image
Type of Preparation:


Endocervical adenocarcinoma in situ (AIS)

Cytomorphologic Criteria:
Sheet of cells with enlarged, hyperchromatic nuclei, increased N/C ratios and feathering at the periphery of the sheet.

Explanatory Notes:
Note the monotony of the hyperchromasia in the nuclei in contrast to the more variable nuclear changes seen in tubal metaplasia.

Endocervical adenocarcinoma in situ

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 118 19%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 55 9%
ASC-US # people picked ASC-US 0 0%
ASC-H # people picked ASC-H 2 0%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 11 2%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 2 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 147 24%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 73 12%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 165 27%
Adenocarcinoma # people picked Adenocarcinoma 40 7%
613 interpretations were submitted.

See Also: thumbnail for figure DS-312.jpg
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