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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP

Magnification:
Medium

Clinical History:
52 year old female on estrogenic hormone therapy.

Interpretation:
Atypical endometrial cells

Cytomorphologic Criteria:
Three-dimensional group of small cells with crowded round or oval nuclei.

Explanatory Notes:
In liquid-based preparations, the evaluation of individual cell features may be difficult in the dense three-dimensional clusters.

Follow-up:
Endometrial hyperplasia

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 233 42%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 39 7%
ASC-US # people picked ASC-US 0 0%
ASC-H # people picked ASC-H 9 2%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 18 3%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 2 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 111 20%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 119 21%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 22 4%
Adenocarcinoma # people picked Adenocarcinoma 8 1%
 
561 interpretations were submitted.

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