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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP


Clinical History:
63 year old woman with postmenopausal bleeding

Atypical endometrial cells

Cytomorphologic Criteria:
Aggregate of small cells with slightly enlarged round or oval nuclei, small nucleoli and finely vacuolated cytoplasm.

Explanatory Notes:
Atypical endometrial cells may be associated with the presence of a wide variety of processes, including polyps, chronic endometritis, hyperplasia, and carcinoma.

Adenocarcinoma of the endometrium, grade I

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 2 0%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 34 6%
ASC-US # people picked ASC-US 1 0%
ASC-H # people picked ASC-H 3 1%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 81 14%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 2 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 17 3%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 157 27%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 17 3%
Adenocarcinoma # people picked Adenocarcinoma 271 46%
585 interpretations were submitted.

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