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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
Medium
Interpretation:
Atypical endocervical cells, NOS, HSIL
Cytomorphologic Criteria:
Cluster of cells showing crowding and overlapping of nuclei, nuclear enlargement, chromocenters, and small nucleoli.
Explanatory Notes:
HSIL involving gland spaces may present as contoured clusters that mimic the appearance of glandular lesions. Note the absence of elongated nuclei, feathering, rosettes, and pseudostratified strips, features that are typically associated with endocervical AIS.
Follow-up:
High grade squamous intraepithelial lesion only
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Bethesda Interobserver Reproducibility Data:
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