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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
Medium
Clinical History:
39 year old woman, routine Pap smear, no LMP date given
Interpretation:
Atypical endocervical cells, NOS
Cytomorphologic Criteria:
Sheet of cells with enlarged round or oval nuclei with prominent nucleoli. Chromatin is finely granular and evenly distributed but occasional chromocenters are seen. Cell borders are well-defined. Mitotic figures are noted.
Explanatory Notes:
In some cases, atypical glandular cells associated with benign processes may be difficult to differentiate from neoplastic processes, especially when mitotic activity is prominent.
Follow-up:
ECC and multiple follow-up Pap smears over three years were negative and the patient have no other gynecologic findings. In view of the benign follow-up, the cytologic atypia and mitotic activity are thought to represent endocervical repair
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Bethesda Interobserver Reproducibility Data:
See Also:
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