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Atlas Interpretation:
Interpreted image
Type of Preparation:


Squamous cell carcinoma

Cytomorphologic Criteria:
Cells on the left with scant cytoplasm display nuclei with irregularly distributed, coarsely granular chromatin and prominent nucleoli. On the right, lysed blood and a stripped nucleus, tumor diathesis, is evident.

Explanatory Notes:
Invasive carcinoma with prominent nucleoli may suggest adenocarcinoma; however, in this case centrally located nuclei and flat arrangement of cells is consistent with squamous cell carcinoma.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 16 3%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 10 2%
ASC-H # people picked ASC-H 13 2%
LSIL # people picked LSIL 0 0%
HSIL # people picked HSIL 24 4%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 249 43%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 19 3%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 7 1%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 12 2%
Adenocarcinoma # people picked Adenocarcinoma 229 40%
579 interpretations were submitted.

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