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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
High
Clinical History:
28 year old woman, LMP 3 weeks, routine exam
Interpretation:
LSIL/HSIL (Borderline)
Cytomorphologic Criteria:
Borderline LSIL/ HSIL. The abnormal cells characterizing moderate dysplasia have a fair amount of cytoplasm compared to severe dysplasia/ CIN3, but less than that in LSIL cells. These cells are at the borderline of what may be interpreted as LSIL by some and HSIL by others.
Explanatory Notes:
While the majority of SIL cases can be classified as HSIL or LSIL, in occasional cases, the distinction between LSIL and HSIL may not be possible. However note that mildly dysplastic cells are often seen in slide preparations diagnostic of more severe lesions. Histologic follow-up of such cases is LSIL or if HSIL, it tends to be CIN 2 (moderate dysplasia).
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Bethesda Interobserver Reproducibility Data:
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