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Atlas Interpretation:
Type of Preparation: ThinPrep/ LBP
Magnification: High
Clinical History: 31 year old
Interpretation:
HSIL
Cytomorphologic Criteria: A cluster of HSIL cells. Important features of high grade squamous intraepithelial lesions are enlarged, centrally placed nuclei, hyperchromasia, and irregular nuclear membranes.
Explanatory Notes: The presence of koilocytes in other cells on the smear supports an interpretation of squamous intraepithelial lesion. In this case HSIL is present, and the highest grade of abnormality present in the smear is what should be reported.
Follow-up: Biopsy- CIN 3
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Bethesda Interobserver Reproducibility Data:
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