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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
High

Interpretation:
SIL

Cytomorphologic Criteria:
SIL- ?keratinizing dysplasia? .Dysplastic cells with keratinized cytoplasm, hyperchromasia, coarsely granular chromatin, and irregular nuclear membranes are consistent with HSIL. SIL- grade may be difficult to determine in case of "keratotic" squamous lesions.

Explanatory Notes:
Classification of atypical keratinized cells depends on the degree of nuclear abnormality, nuclear-cytoplasmic ratio and to some extent, pleomorphism of cell shape.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 0 0%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 48 9%
ASC-H # people picked ASC-H 60 12%
LSIL # people picked LSIL 101 20%
HSIL # people picked HSIL 156 30%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 148 29%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 1 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
514 interpretations were submitted.

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