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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
High
Interpretation:
HSIL
Cytomorphologic Criteria:
Loose aggregate of HSIL cells with some variation in cell size and N/C ratios, irregular nuclear membranes and granular chromatin. Note that some of the metaplastic cells still show mucin/ endocervical features.
Explanatory Notes:
Single dysplastic cells in a streaming pattern, especially at low power may mimic histiocytes A cluster such as this may raise the differential diagnosis of squamous metaplastic cells under lower magnification. Attention to nuclear details is essential to make these distinctions.
Follow-up:
Biopsy was CIN 3 (carcinoma in situ/ sever dysplasia)
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Bethesda Interobserver Reproducibility Data:
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