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Atlas Interpretation:
Interpreted image
Type of Preparation:
SurePath/ LBP


Clinical History:
18 year old

ASC-US vs LSIL (Borderline)

Cytomorphologic Criteria:
Several cells in this group exhibit changes suggestive of koilocytes. Nuclei are only slightly enlarged and do not meet the criteria for LSIL (3 times larger than an intermediate nucleus). Nuclear features are borderline between those required for ASC-US and LSIL.

Explanatory Notes:
Some of these cellular alterations can be seen in a reactive process; however, due to the slight nuclear enlargement, hyperchromasia, and cytoplasmic changes, an interpretation ASC-US may be more appropriate.

Follow-up was CIN 1 (mild dysplasia)

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 220 45%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 189 39%
ASC-H # people picked ASC-H 0 0%
LSIL # people picked LSIL 76 16%
HSIL # people picked HSIL 0 0%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 0 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
485 interpretations were submitted.

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