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Atlas Interpretation:
Type of Preparation: Conventional
Magnification: Medium
Interpretation:
ASC-US vs LSIL
Cytomorphologic Criteria: Nuclei are hyperchromatic with fine chromatin and smooth membranes. Nuclear features are borderline between those required for ASC-US and LSIL.. Cell sizes vary with the smallest cell resembling a benign metaplastic cell.
Explanatory Notes: Some cells contain enlarged nuclei but chromatin is similar in all cells. While there is some "atypia" , clear cut evidence for an interpretation of LSIL is lacking.
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Bethesda Interobserver Reproducibility Data:
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