NCI Bethesda System 2001 logo American Society of Cytopathology logo
 Main Page 
 Search By:
   Atlas Chapter 
   Atlas Figure # 
   Terminology Table 
   Keyword 
   Preparation Type 
   BIRP Images 
 Self-Test 
 Acknowledgments 
 Links 
 Feedback 

[Back to Listing]
Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
Medium

Interpretation:
ASC-US vs LSIL

Cytomorphologic Criteria:
Nuclei are hyperchromatic with fine chromatin and smooth membranes. Nuclear features are borderline between those required for ASC-US and LSIL.. Cell sizes vary with the smallest cell resembling a benign metaplastic cell.

Explanatory Notes:
Some cells contain enlarged nuclei but chromatin is similar in all cells. While there is some "atypia" , clear cut evidence for an interpretation of LSIL is lacking.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 39 8%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 231 47%
ASC-H # people picked ASC-H 14 3%
LSIL # people picked LSIL 190 39%
HSIL # people picked HSIL 14 3%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 0 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
488 interpretations were submitted.

[Back to Listing]
Definitions of terms used in this site