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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
Medium

Interpretation:
LSIL

Cytomorphologic Criteria:
Cells with keratinized cytoplasm, slight nuclear enlargement and hyperchromasia ("atypical parakeratosis") interpretation as LSIL is based on nuclear features.

Explanatory Notes:
"Parakeratosis" is a descriptive term used for abnormal keratinization of the cytoplasm but it is not an interpretation and is not part of the Bethesda terminology. "Parakeratotic" changes may be seen in cells without nuclear abnormalities and in SIL.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 20 4%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 1 0%
ASC-US # people picked ASC-US 167 31%
ASC-H # people picked ASC-H 101 19%
LSIL # people picked LSIL 123 23%
HSIL # people picked HSIL 108 20%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 20 4%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
540 interpretations were submitted.

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