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Atlas Interpretation:
Type of Preparation:
ThinPrep/ LBP
Magnification:
High
Clinical History:
32 year old, LMP: 20 days, routine screening
Interpretation:
LSIL
Cytomorphologic Criteria:
HPV nuclear and cytoplasmic changes (binucleation and koilocytosis) are consistent with LSIL. Note that in addition to perinuclear cavitation, nuclear abnormalities as seen here are required to make an interpretation of LSIL.
Explanatory Notes:
Nuclear size is only 2 times larger than intermediate nuclei, but chromatin pattern is granular and nuclear membranes are irregular.
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Bethesda Interobserver Reproducibility Data:
See Also:
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