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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP


Clinical History:
32 year old female, LMP- 2 weeks ago


Cytomorphologic Criteria:
Large, multinucleated dysplastic cells with "mature" cytoplasm and distinct cell borders. Nucleus shows enlargement which is > 3X intermediate nuclei, hyperchromasia, pleomorphism of size and shape. No nucleoli seen.

Explanatory Notes:
Note the overall large cell size, well-defined cytoplasm and multinucleation. .

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 18 3%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 30 5%
ASC-H # people picked ASC-H 21 4%
LSIL # people picked LSIL 346 59%
HSIL # people picked HSIL 153 26%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 13 2%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 2 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
583 interpretations were submitted.

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