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Atlas Interpretation:
Interpreted image
Type of Preparation:


NILM: Histiocytes

Cytomorphologic Criteria:
Streaming pattern of single cells with round, ovoid, and bean-shaped nuclei. These cells are histiocytes with eccentric round to oval nuclei and foamy cytoplasm.

Explanatory Notes:
These cells possess fine cytoplasmic vacuoles that may resemble degenerative vacuoles sometimes found in normal metaplasia, ASC-H, and HSIL. Typically, cells of squamous lineage are polygonal in shape and possess dense cytoplasm. (Compare with ASC-H and HSIL in mucus).

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 253 55%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 3 1%
ASC-US # people picked ASC-US 17 4%
ASC-H # people picked ASC-H 85 18%
LSIL # people picked LSIL 6 1%
HSIL # people picked HSIL 93 20%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 0 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 4 1%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 3 1%
464 interpretations were submitted.

See Also: thumbnail for figure 4_20.jpg
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