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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP

Magnification:
High

Clinical History:
32 yr old woman, HIV+. Anal-rectal sample

Interpretation:
LSIL

Cytomorphologic Criteria:
2 year follow up -- developed anal HSIL; and also high grade cervical and vulvar disease.

Explanatory Notes:
LSIL showing nuclear enlargement and HPV changes. The cytologic criteria used in evaluating anal specimens are similar to those for the cervix.

Follow-up:
Anal samples often display more degenerative changes and evidence of cytoplasmic keratinization than seen with cervical samples


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