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Atlas Interpretation:
Interpreted image
Type of Preparation:
ThinPrep/ LBP


Clinical History:
32 yr old woman, HIV+. Anal-rectal sample


Cytomorphologic Criteria:
2 year follow up -- developed anal HSIL; and also high grade cervical and vulvar disease.

Explanatory Notes:
LSIL showing nuclear enlargement and HPV changes. The cytologic criteria used in evaluating anal specimens are similar to those for the cervix.

Anal samples often display more degenerative changes and evidence of cytoplasmic keratinization than seen with cervical samples

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