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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
High

Clinical History:
Post-Menopausal

Interpretation:
ASC-H

Cytomorphologic Criteria:
Immature cells have high N:C ratios and irregular nuclear contours.

Explanatory Notes:
Such cells may be seen in atrophy, but the differential includes a high grade lesion. Repeat sampling following a course of estrogen may clarify the findings.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 4 1%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 31 6%
ASC-H # people picked ASC-H 148 29%
LSIL # people picked LSIL 26 5%
HSIL # people picked HSIL 296 58%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 1 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 1 0%
 
507 interpretations were submitted.

See Also: thumbnail for figure DS-401.jpg
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