NCI Bethesda System 2001 logo American Society of Cytopathology logo
 Main Page 
 Search By:
   Atlas Chapter 
   Atlas Figure # 
   Terminology Table 
   Keyword 
   Preparation Type 
   BIRP Images 
 Self-Test 
 Acknowledgments 
 Links 
 Feedback 

[Back to Listing]
Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
High

Clinical History:
50 year old postmenopausal woman, prior abnormal Pap elsewhere

Interpretation:
ASC-H

Cytomorphologic Criteria:
Atypical keratinized cells with smudged chromatin present in an atrophic background. Cells are suggestive of a high grade lesion however poor preservation precludes definitive interpretation.

Follow-up:
Moderate dysplasia on repeat Pap smear and cervical biopsy after topical estrogen therapy

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 28 5%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 26 5%
ASC-H # people picked ASC-H 64 12%
LSIL # people picked LSIL 4 1%
HSIL # people picked HSIL 61 12%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 339 65%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
522 interpretations were submitted.

See Also: thumbnail for figure DS-28.jpg
[Back to Listing]
Definitions of terms used in this site