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Atlas Interpretation:
Interpreted image
Type of Preparation:


Clinical History:
50 year old postmenopausal woman, prior abnormal Pap elsewhere


Cytomorphologic Criteria:
Atypical keratinized cells with smudged chromatin present in an atrophic background. Cells are suggestive of a high grade lesion however poor preservation precludes definitive interpretation.

Moderate dysplasia on repeat Pap smear and cervical biopsy after topical estrogen therapy

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 28 5%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 26 5%
ASC-H # people picked ASC-H 64 12%
LSIL # people picked LSIL 4 1%
HSIL # people picked HSIL 61 12%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 339 65%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 0 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
522 interpretations were submitted.

See Also: thumbnail for figure DS-28.jpg
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