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Atlas Interpretation:
Type of Preparation:
ThinPrep/ LBP
Magnification:
Medium
Clinical History:
69 year old postmenopausal female. S/P TAH/BSO for Stage 2 endometrial adenocarcinoma. H/O VAIN 10 years ago. Vaginal ThinPrep
Interpretation:
ASC-H
Cytomorphologic Criteria:
Atypical multinucleated cell.
Explanatory Notes:
Atypical cells may be seen in atrophy, but the differential includes a high grade lesion. Repeat sampling following a course of estrogen may clarify the findings.
Follow-up:
Vaginal cuff biopsies and repeat Pap test 2 months later showed severe dysplasia/CIS (CIN 3)
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Bethesda Interobserver Reproducibility Data:
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