Type of Preparation: SurePath/ LBP Magnification: High Interpretation: NILM: Cellular changes consistent with Herpes simplex virus Cytomorphologic Criteria: Large multinucleated epithelial cell with molded nuclei. Note ground glass appearance due to intranuclear viral particles and enhancement of the nuclear envelope caused by peripheral margination of the chromatin. Explanatory Notes: Multinucleated epithelial cells are not always present--mononucleate cells with viral changes may be the only finding.