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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
Medium

Interpretation:
NILM: Cellular changes consistent with Herpes simplex virus

Cytomorphologic Criteria:
Nuclei showing "ground-glass" appearance. Multinucleation, nuclear molding, and dense eosinophilic intranuclear inclusions surrounded by a halo are also seen.

Explanatory Notes:
"Ground-glass" appearance is due to intranuclear viral particles and enhancement of nuclear envelope caused by peripheral chromatin margination.

Bethesda Interobserver Reproducibility Data:
NILM: Negative for Intraepithelial Lesion or Malignancy # people picked NILM: Negative for Intraepithelial Lesion or Malignancy 529 96%
Endometrial cells in a woman >= 40 # people picked Endometrial cells in a woman >= 40 0 0%
ASC-US # people picked ASC-US 9 2%
ASC-H # people picked ASC-H 1 0%
LSIL # people picked LSIL 9 2%
HSIL # people picked HSIL 1 0%
Invasive Squamous Cell Carcinoma # people picked Invasive Squamous Cell Carcinoma 0 0%
Atypical Endocervical Cells # people picked Atypical Endocervical Cells 0 0%
Atypical Endometrial Cells # people picked Atypical Endometrial Cells 1 0%
Adenocarcinoma in situ (AIS), Endocervical # people picked Adenocarcinoma in situ (AIS), Endocervical 0 0%
Adenocarcinoma # people picked Adenocarcinoma 0 0%
 
550 interpretations were submitted.

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