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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
Medium
Interpretation:
NILM: Cellular changes consistent with Herpes simplex virus
Cytomorphologic Criteria:
Nuclei showing "ground-glass" appearance. Multinucleation, nuclear molding, and dense eosinophilic intranuclear inclusions surrounded by a halo are also seen.
Explanatory Notes:
"Ground-glass" appearance is due to intranuclear viral particles and enhancement of nuclear envelope caused by peripheral chromatin margination.
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Bethesda Interobserver Reproducibility Data:
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