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Atlas Interpretation:
Type of Preparation: ThinPrep/ LBP
Magnification: High
Clinical History: 63 year old postmenopausal woman with a hx of malignant lymphoma presents with an enlarged cervix; patient on HRT
Interpretation:
Other Malignant Neoplasms: Malignant lymphoma
Cytomorphologic Criteria: Scattered atypical lymphoid cells with clumped chromatin and conspicuous nucleoli.
Explanatory Notes: Notice the resemblance of these cells to the single cells of small cell undifferentiated carcinoma in liquid preparations. The possibility of follicular cervicitis that presents with a polymorphous lymphocytic population and tingible body macrophages should also be considered in the differential diagnosis.
Follow-up: Involvement of cervix by lymphoma confirmed by biopsy
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