Type of Preparation: Conventional Magnification: High Clinical History: 42 year old perimenopausal woman presents with irregular bleeding and an enlarged uterus Interpretation: Other Malignant Neoplasms: Sarcoma Cytomorphologic Criteria: This loose syncytial group of malignant cells with variable nuclear features and prominent nucleoli shows no characteristic epithelial or mesenchymal features. Explanatory Notes: Most sarcomas present with undifferentiated cells and may be recognized as malignant neoplasms that cannot be further subclassified. The differential diagnosis includes a poorly differentiated carcinoma. Follow-up: High grade sarcoma on hysterectomy