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Atlas Interpretation:
Interpreted image
Type of Preparation:


Clinical History:
35 year old woman with history of an abnormal Pap at another institution

endocervical adenocarcinoma in situ, intestinal type (AIS)

Cytomorphologic Criteria:
Cluster of abnormal glandular cells with nuclear crowding and overlap, elongated nuclei, and inconspicuous nucleoli. Note numerous goblet-type cells.

Explanatory Notes:
Although uncommon, variant patterns of AIS exist (e.g., intestinal, endometrioid, clear cell) and may show morphologic features that differ from those seen in the "classic" endocervical form.

Endocervical adenocarcinoma in situ, intestinal pattern

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