Type of Preparation: Conventional Magnification: High Clinical History: 58 year old woman, LMP 8 years, postmenopausal bleeding Interpretation: Adenocarcinoma, Endometrial Cytomorphologic Criteria: Large aggregate of small cells with irregular chromatin distribution, small nucleoli, poorly defined finely vacuolated cytoplasm in a watery background. Explanatory Notes: In conventional smears, endometrial adenocarcinoma tends to be associated with a thin watery diathesis in contrast to the bloody, necrotic background often seen with endocervical adenocarcinoma. Follow-up: Adenocarcinoma of the endometrium