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Atlas Interpretation:
Interpreted image
Type of Preparation:
Conventional

Magnification:
High

Clinical History:
30 year old woman with IUD

Interpretation:
NILM: Reactive Cellular changes associated with IUD

Cytomorphologic Criteria:
Small cluster of glandular cells with cytoplasmic vacuoles displacing nuclei in a clean background.

Explanatory Notes:
The amount of cytoplasm varies and frequently large vacuoles may displace the nucleus, creating a signet -ring appearance. The cells may be shed as clusters or singly. Clusters such as these may mimic cells from adenocarcinoma. One should diagnose adenocarcinoma with caution in the presence of an IUD. If in doubt, consider repeat sampling after removal of the IUD. Single cells may mimic high grade SIL. One needs to look for the morphologic spectrum of abnormalities associated with SIL.


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