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Atlas Interpretation:
Type of Preparation: Conventional
Magnification: High
Clinical History: 89 year old woman with hx of high grade urothelial carcinoma diagnosed two years previously
Interpretation:
Other malignant neoplasms: metastatic transitional cell carcinoma
Cytomorphologic Criteria: Single and small aggregates of malignant cells are diagnostic of a poorly differentiated carcinoma. A mitotic figure and a bloody background are also noted. The findings are compatible with the patient's previous high grade tumor.
Explanatory Notes: Transitional cell carcinoma is one of the most commonly encountered secondary tumors in cytologic cervical samples, and may involve the cervix/ vagina by direct extension or as a pagetoid spread to the vagina. Its cytologic features may overlap with squamous cell carcinoma.
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