NCI Bethesda System 2001 logo American Society of Cytopathology logo
 Main Page 
 Search By:
   Atlas Chapter 
   Atlas Figure # 
   Terminology Table 
   Keyword 
   Preparation Type 
   BIRP Images 
 Self-Test 
 Acknowledgments 
 Links 
 Feedback 

[Back to Listing]
Atlas Interpretation:
Interpreted image
Type of Preparation:
SurePath/ LBP

Magnification:
Medium

Clinical History:
35 year old

Interpretation:
HSIL

Cytomorphologic Criteria:
On low magnification, this large "hyperchromatic" cluster of cells displays enlarged nuclei and a high nuclear to cytoplasmic ratio. The dense cytoplasm suggests a squamous origin. The pattern is consistent with CIS.

Explanatory Notes:
As in conventional smears, crowded hyperchromatic cell groups should be examined with care. If a squamous abnormality is suspected, a thorough search for single dysplastic cells in the background is warranted. SIL occasionally presents morphologically as spindle cells.

Follow-up:
Biopsy-CIN 3 (severe dysplasia/carcinoma in situ)


See Also: thumbnail for figure JC-HSIL10.jpg
[Back to Listing]
Definitions of terms used in this site