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Atlas Interpretation:
Type of Preparation:
Conventional
Magnification:
Medium
Clinical History:
A 45 year old female for a routine visit
Interpretation:
NILM
Cytomorphologic Criteria:
Lower uterine segment (LUS). Large tissue fragments with a biphasic pattern of glands and spindle cells. Densely packed spindle cells are seen with glands embedded within. Glands are simple, nonbranching, with indistinct cytoplasm and round uniform nuclei.
Explanatory Notes:
The lower uterine segment (LUS) can easily be sampled if the endocervical sampling device is pushed into the endocervical canal far enough to reach the LUS. In isolation, the epithelial fragments may be mistaken for endocervical adenocarcinoma, endocervical adenocarcinoma in situ, tubal metaplasia or reactive endocervical cells. The spindle cells alone may also appear as "hyperchromatic groups" and cause concern. Abraded LUS does not carry the same significance as exfoliated endometrial cells and should not be reported.
Follow-up:
Normal follow up for 5 years
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Bethesda Interobserver Reproducibility Data:
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