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Atlas Interpretation:
Type of Preparation:
ThinPrep/ LBP
Magnification:
High
Clinical History:
43 year old whose LMP not available. She has no symptoms of bleeding
Interpretation:
Endometrial cells are present in a woman >= 40 years of age.
Negative for squamous intraepithelial lesion. (See Note)
Note: Endometrial cells after age 40, particularly out of phase or after menopause may be associated with benign endometrium, hormonal alterations and less commonly, endometrial /uterine abnormalities. Clinical correlation is recommended
Cytomorphologic Criteria:
Three dimensional groups with depth of focus. Dark stromal cells are present internally. Epithelial cells surround the cluster in a "double contour." Nuclear features of epithelial and stromal cells are more readily apparent in ThinPrep specimens than conventional smears.
Explanatory Notes:
Exfoliated glandular endometrium may be seen when evaluating Pap tests. When endometrial cells are encountered in a woman 40 or older, they are uncommonly associated with significant pathology. Rarely, typical endometrial cells may be associated with an asymptomatic endometrial carcinoma in this age group. Because of this association, all glandular endometrial cells are reported in women 40 years and over.
Follow-up:
No symptoms for 3 years following this Pap preparation. Subsequent Pap tests have been negative
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Bethesda Interobserver Reproducibility Data:
See Also:
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