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Atlas Interpretation:
Interpreted image
Type of Preparation:



Cytomorphologic Criteria:
HSIL (CIS) cells are seen in a syncytial arrangement of cells with hyperchromatic nuclei and a high nuclear to cytoplasmic ratio. The loss of polarity and dense cytoplasm are consistent with CIS .

Explanatory Notes:
CIS can be seen in a syncytial pattern as demonstrated here or in smaller groups or as isolated cells. Additionally the cytoplasm in HSIL cells maybe dense (metaplastic), immature/ lacy/ non-metaplastic or keratinized. Compare this pattern of CIS with images showing endocervical gland involvement by HSIL.

See Also: thumbnail for figure DW64.jpg
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