Type of Preparation: Conventional Magnification: Medium Interpretation: LSIL Cytomorphologic Criteria: Mature squamous cells display enlarged nuclei with granular chromatin and large cytoplasmic cavitations consistent LSIL and human papillomavirus cytopathic effect. Explanatory Notes: Cytoplasmic clearing consistent with koilocytotic change is evident in some cells. A sharp inner edge of the cavitation characterizes koilocytes.