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Atlas Interpretation:
Type of Preparation: Conventional
Magnification: High
Adequacy Description:
Air Drying in HSIL CIN 2
Cytomorphologic Criteria: Air-drying artifact in cells suggestive of HSIL. Enlarged, focally pale nuclei with indistinct chromatin. The nuclei are crowded and lack an orderly architectural arrangement, and some cells appear hyperchromatic. Specimens with air-drying may be difficult to specifically categorize.
Explanatory Notes: The laboratory may choose to mention air drying as a quality indicator when abnormal-appearing cells are difficult to categorize. However, any specimen with abnormal cells is by definition satisfactory.
Follow-up: Colposcopy and biopsy 6 months later was interpreted as "Mild dysplasia with koilocytosis." Discrepancies such as this can be expected to occur sometimes, regardless of the quality of the preparation. The delay between the Pap and the biopsy may also play a role in such discrepancies
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