THE 2001 BETHESDA SYSTEM

• SPECIMEN TYPE
  Indicate conventional smear (Pap smear) vs. liquid-based preparation vs. other
   
• SPECIMEN ADEQUACY
   
  • Satisfactory for evaluation
    (describe presence or absence of endocervical/transformation zone component and any other quality indicators, e.g., partially obscuring blood, inflammation, etc)
  • Unsatisfactory for evaluation (specify reason)
    • Specimen rejected/not processed (specify reason)
    • Specimen processed and examined, but unsatisfactory for evaluation of epithelial abnormality because of (specify reason)
  
  
• INTERPRETATION/RESULT
   
  • NEGATIVE FOR INTRAEPITHELIAL LESION OR MALIGNANCY
    (when there is no cellular evidence of neoplasia, state this in the General Categorization above and/or in the Interpretation/Result section of the report, whether or not there are organisms or other non-neoplastic findings)
    • Organisms
      • Trichomonas vaginalis
      • Fungal organisms morphologically consistent with Candida spp
      • Shift in flora suggestive of bacterial vaginosis
      • Bacteria morphologically consistent with Actinomyces spp
      • Cellular changes consistent with Herpes simplex virus
    • Other non-neoplastic findings (Optional to report; list not inclusive)
      • Reactive cellular changes associated with:
        • Inflammation (includes typical repair)
        • Radiation
        • Intrauterine contraceptive device (IUD)
      • Glandular cells status post hysterectomy
      • Atrophy
    
    
  • OTHER
    • Endometrial cells (in a woman >= 40 years of age)
      (Specify if ‘negative for squamous intraepithelial lesion’)
    
    
  • EPITHELIAL CELL ABNORMALITIES
    • Squamous cell
      • Atypical squamous cells
        • Of undetermined significance (ASC-US)
        • Cannot exclude HSIL (ASC-H)
      • Low grade squamous intraepithelial lesion (LSIL)
        Encompassing: HPV/mild dysplasia/CIN 1
      • High grade squamous intraepithelial lesion (HSIL)
        Encompassing: moderate and severe dysplasia, CIS; CIN 2 and CIN 3
        • With features suspicious for invasion (if invasion is suspected)
      • Squamous cell carcinoma
    • Glandular cell
      • Atypical
        • Endocervical cells, NOS or specify in comments
        • Endometrial cells, NOS or specify in comments
        • Glandular cells, NOS or specify in comments
      • Atypical
        • Endocervical cells, favor neoplastic
        • Glandular cells, favor neoplastic
      • Endocervical adenocarcinoma in situ
      • Adenocarcinoma
        • Endocervical
        • Endometrial
        • Extrauterine
        • Not otherwise specified (NOS)
    
    
  • OTHER MALIGNANT NEOPLASMS (specify)
  
  
• ANCILLARY TESTING
   
• AUTOMATED REVIEW
   
• EDUCATIONAL NOTES AND SUGGESTIONS (optional)